mouse

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14 Cards. Created by tyrrielle doucette ().
 
Term  
Definition

Uses in Research

• The laboratory mouse today is purposely bred for research • The different strains of mice in laboratories are defined by ecological and genetic characteristics • Outbred, inbred, congenic, and transgenic stock are strains defined by genetic characteristics

what are the different strains of genetics

o Outbred strains are the result of random mating o Inbred strains are the result of brother/sister, father/daughter, mother/son matings for a minimum of 20 consecutive generations

o Congenic strains o Transgenic strains

what kind of mice are used

• Axenic, or germ-free, animals are derived from hysterectomy, free from infection by any microorganisms• Gnotobiotic • Specific pathogen-free (SPF) and viral antibody-free (VAF) animals are those free from specific pathogenic organisms • Barrier-sustained • Conventional animals are those housed with no special precautions

what is barbering? what should you do when it happens

dominant mouse in a group will remove the facial hair from all the other mice in the cage source of stress to the submissive mice, so the “barber” should be removed from the cage

What is the whitten effect

: female mice are exposed to a male mouse, some go come into estrus within 72 hours

what is the bruce effect

if a recently bred female is exposed to another male, the pregnancy will not take and she will return to estrus in 4-5 days

where to give a SQ injection/IM injection/IP injection/IV injection

over the shoulder area/inner or posterior thigh muscle/lower right quadrant of abdomen/ lateral tail vein, saphenous v.

Where to collect blood? What kid of procedure is it

o Cardiac Considered a terminal procedure because of potential damage to the heart

What are some signs of pain and distress

• Hunched posture • Lethargy, depression, and withdrawal from the group • Change in behavior

What are respiratory disease

o Viral or Bacterial o Clinical signs are weight loss, ruffled hair coat, hunched posture, anorexia, dyspnea, chattering and sudden death

What causes Tyzzer disease

Clostridium

What causes EDIM (• Epizootic Diarrhea of Infant Mice )

o Caused by a rotavirus that affects suckling mice

How to treat Pinworm disease

o Treatment: Deworm; sanitize the environment

Clinical signs of Mites

alopecia, pruritus, and dermatitis